Overcoming Translational Challenges in DR & DME: Holistic Approaches for Better Models
Time: 2:00 pm
day: Day One
Details:
- Develop appropriate in vivo models that accurately replicate human disease conditions for diabetic retinopathy (DR) and diabetic macular edema (DME), addressing the limitations and variability of current rodent models
- Integrate computational and in vitro methods alongside in vivo studies to create a comprehensive, holistic approach for predicting drug efficacy and improving the translational success of preclinical findings
- Enhance collaboration between basic scientists and clinicians to refine these models, ensuring they capture the complex phenotypes of DR and DME, ultimately facilitating smoother transitions to clinical trials
