Exploring Current Advancements in In Vivo Models for Accurate Representation of the Retinal Vascular Microenvironment for Improved Translation into Humans
Time: 1:30 pm
day: Conference Day 1
Details:
- Examining the unmet need for high-fidelity animal models of complex, multiple factorial and/or polygenic diseases such as nAMD
- Understanding the challenges with current in vivo models left to age for years, fed special diets or exposed to cigarette smoke to introduce external modulators
- Navigating the required improvements in preclinical in vivo models to accurate replicate human choroidal neovascularization for better translation of therapeutics
- Validating non-animal (in vitro) preclinical models and discussing if they are realistic alternatives to non-human primates
